What is Hydroxocobalamin Therapy and its Cost?

Understanding the Benefits, Uses, and Costs of Hydroxocobalamin in India

Feeling tired all the time or struggling with unexplained nerve issues? Hydroxocobalamin therapy might be the solution your body’s been craving. This potent form of vitamin B12 is not just a supplement; it is a medically approved treatment for vitamin B12 deficiency and cyanide poisoning, administered under professional supervision. This treatment also helps support nerve function, red blood cell production, and detoxification in emergency cases.

What is Hydroxocobalamin Therapy?

Hydroxocobalamin therapy is a medical treatment that helps increase vitamin B12 levels in the body. It is also used to treat cyanide poisoning. In such cases, it acts as a binding agent. It joins with cyanide to form cyanocobalamin, which the body removes through urine.

Hydroxocobalamin is typically administered intravenously for cyanide poisoning, often as a 5 g infusion over 15 minutes, without a specific requirement for dextrose solution.

In India, Hydroxocobalamin is produced by several pharmaceutical companies, such as Trineurosol HP, Nuray Chemicals Private Limited, Supriya Lifescience, etc. The products are typically available in 1 mg/ml strength, are distributed in vials or ampoules and are used under medical supervision.

Which Conditions Does Hydroxocobalamin Treat?

Doctors use Hydroxocobalamin to treat several health conditions linked to vitamin B12 deficiency or toxin exposure. These include:

• Vitamin B12 Deficiency Anaemia: Caused by a low red blood cell count, symptoms may include fatigue, memory issues, tingling in limbs, sore mouth, and depression.
• Tobacco Amblyopia& Leber’s Atrophy: Hydroxocobalamin may be used off-label for conditions like Leber’s optic atrophy and tobacco amblyopia, but these uses are not FDA-approved and should be guided strictly by specialist consultation.

How Much Does Hydroxocobalamin Cost in India?

The price of Hydroxocobalamin injections in India ranges from Rs. 14 to Rs. 110 per ampoule, depending on the brand and supplier. Brands like Trineurosol HP may cost as low as Rs. 14, while others can go up to Rs. 110.

Source Naturals prices its HydroxoCobalamin lozenges at around Rs. 1,245.41 for 120 tablets. Although injections are cheaper per dose, they require a doctor’s supervision, while lozenges are more convenient but costlier.

Is Hydroxocobalamin Better as an Injection or Tablet?

Both forms are effective, but they serve different needs. Injections are ideal for serious B12 deficiencies or absorption issues and must be given by a healthcare professional. Oral supplements, like lozenges, are convenient and suitable for mild deficiencies or maintenance.

Studies show that high-dose oral B12 (1,000–2,000 mcg) can be just as effective as injections in many cases.

What are the Possible Side Effects of Hydroxocobalamin?

Common side effects include nausea, vomiting, diarrhoea, headache, dizziness, and skin reactions like redness or pain at the injection site. Rarely, acne or allergic responses may occur. If any symptom persists or worsens, consult your doctor promptly for further guidance or to adjust the treatment.

While Hydroxocobalamin is an effective treatment for B12 deficiency, a healthy lifestyle can further support recovery. Include vitamin B12-rich foods like eggs, dairy, meat, fish, and fortified cereals in your diet. For vegans, plant-based options such as nutritional yeast, plant milks, and fortified products are helpful.

Avoid alcohol and smoking, exercise regularly, and maintain a balanced diet to keep your B12 levels steady and support overall well-being.