How is Polycythaemia Vera Treated in Hyderabad?

Managing Polycythaemia Vera with Expert Care in Hyderabad

Polycythaemia vera (PV) is an uncommon form of blood cancer called a myeloproliferative neoplasm (MPN). With several multi-speciality hospitals and haematology facilities providing excellent diagnostics and treatment, Hyderabad is well-positioned to help patients deal with this disorder.

From efficient lab analysis to tailored treatment options, healthcare facilities in the city strive to manage PV's symptoms, minimise the risk of blood clots, and enhance long-term health outcomes. Continue reading to learn more about this condition, including its treatment options in Hyderabad.

How to Treat Polycythaemia Vera in Hyderabad?

Though there is no cure for PV, treatment involves reducing the level of red blood cells, alleviating symptoms, and preventing blood clots. In Hyderabad, haematologists at some of the best hospitals offer the following treatments:

• Phlebotomy : This is typically the initial treatment for PV. It is a procedure of frequently drawing off an amount of blood from a vein to lower red blood cell levels and total blood volume. This thins the blood and improves circulation, lowering the chances of clotting.
• Low-Dose Aspirin : Aspirin prevents blood platelets from aggregating, which reduces the occurrence of clots. It also alleviates symptoms such as burning sensations in the hands and feet. However, due to its possible side effects, such as stomach upset or bleeding, it is administered with caution, particularly in patients suffering from ulcers or bleeding disorders.
• Myelosuppressive Medications : If phlebotomy itself is inadequate or the patient is at greater risk for clotting, several medications can be employed to slow the production of blood cells from the bone marrow. These include Hydroxyurea (Hydrea), Interferon-alpha or Ropeginterferon alfa-2b (Besremi), Ruxolitinib (Jakafi), and so on.

How to Diagnose Polycythaemia Vera in Hyderabad?

Diagnosis of polycythaemia vera (PV) involves a comprehensive test that includes blood testing, bone marrow examination, and genetic analysis. The initial step usually involves blood tests that are indicative of too many red blood cells, frequently accompanied by high haemoglobin and haematocrit (the ratio of red blood cells to overall blood volume).

In certain instances, white blood cells or platelets might also be increased. A bone marrow biopsy and aspiration are then conducted to evaluate the production of blood cells. These procedures entail taking samples from the hipbone to determine if there is an overproduction of blood cells or an excess of mature megakaryocytes (cells that produce platelets).

Genetic testing also helps establish a diagnosis by identifying the JAK2 (Janus kinase 2) gene mutation, which is found in the majority of cases of PV. A very low erythropoietin level-a hormone that stimulates red blood cell production-can also help establish the diagnosis.

Hyderabad's healthcare centres offer comprehensive care for individuals with polycythaemia vera, combining innovative diagnostics with tailored treatments. Early detection, continuous follow-up, and professional care enable patients to manage symptoms and lead a fulfilling life effectively.