Tabes dorsalis is a rare neurological disorder that develops slowly over time. It affects movement, balance, and sensation, often causing sharp pain and coordination problems. Read on to learn about everything that this syndrome entails.
Tabes dorsalis is a late-stage neurosyphilis that develops years after the first infection. Syphilis happens due to a bacterium called Treponema pallidum. If the infection is left untreated, it slowly spreads throughout the body. After 10 to 30 years, it damages the spinal cord and brain. When it reaches the spinal cord, it causes tabes dorsalis.
Modern antibiotics, such as penicillin, have made this condition rarer. However, in people who have weak immune systems or those who miss early treatment, syphilis can still progress to this critical stage.
People with tabes dorsalis may experience a combination of sensory, physical and autonomic symptoms that worsen gradually over time. These symptoms result from damage to the dorsal columns of the spinal cord, which are responsible for carrying sensory signals related to touch, vibration and position.
Here are a few of the most common ones:
Doctors diagnose tabes dorsalis by using a mix of medical history, symptoms, and tests. If a patient has a history of untreated syphilis and shows signs of nerve damage, then the doctor may suspect neurosyphilis. Some of the tests include:
An early diagnosis is vital. It can help slow the disease’s progress and reduce damage.
The main treatment for tabes dorsalis is antibiotic therapy. It is generally a high-dose penicillin that is given through an IV. It stops the infection from worsening. However, it cannot reverse the nerve damage that has already been done.
Here are a few other treatments that focus on the management of symptoms:
Neurosyphilis and tabes dorsalis are related yet not the same. Here is a list of some differences based on different aspects between them:
Feature | Neurosyphilis | Tabes Dorsalis |
Type | Broad category | Specific subtype |
Area Affected | Brain, spinal cord, and peripheral nerves | Mainly, the dorsal columns of the spinal cord |
Onset | It can occur at any stage of syphilis | Usually develops 10-30 years after initial infection |
Symptoms | Varies by type (ex., headaches, confusion, stroke-like signs) | Sharp leg pain, poor balance, weak reflexes and sensory loss |
Pupils | May or may not be affected | Often causes Argyll Robertson pupils |
Diagnosis | Blood and CSF tests, imaging, neurological assessment | Same tests, with a focus on sensory and spinal cord symptoms |
Treatment | High-dose antibiotics (ex., penicillin) | Same antibiotics, plus symptom management and rehabilitation |
Tabes dorsalis is a preventable condition. By treating syphilis early on and practising safe behaviours, individuals can avoid this late-stage complication. Here are a few key strategies to reduce this risk:
Routine sexual health check-ups can detect syphilis before it progresses. Sexually active people, especially those with multiple partners or in high-risk groups, should undergo regular screening.
Using condoms and having open conversations with partners about sexual health reduces the chance of contracting syphilis. These precautions are very crucial even when symptoms are not present. This is because syphilis often spreads silently in the early stages.
People already diagnosed with neurological conditions can detect early signs of complications. An early intervention can help to slow down or even stop the development of tabes dorsalis.
Community education plays a crucial role in preventing tabes dorsalis. Public health campaigns help raise awareness about the condition and its long-term consequences, motivating individuals to undergo testing.
Improved access to testing increases the chances of early diagnosis and treatment, particularly among vulnerable populations, ultimately reducing the risk of severe complications.
Tabes dorsalis is a serious but preventable condition. Understanding its causes and symptoms is vital for early detection. A prompt diagnosis is essential to avoid any long-term damage from it.