Should You Take Citrulline Supplements?

Citrulline Malate: Benefits, Side Effects & More

Citrulline therapy, in the context of health and fitness, primarily refers to the use of L-citrulline or citrulline malate supplements. Athletes often take these supplements to improve athletic performance and enhance muscle pumps. Generally, the prices of citrulline supplements in India range from Rs. 269 to Rs. 1,799. 

How Does Citrulline Malate Work Inside the Body?

Citrulline malate supplementation may support nitric oxide production by increasing arginine levels, which can improve blood flow. Some studies suggest it may enhance exercise performance, though results vary depending on activity type and dosage. L-citrulline plays a key role in the urea cycle, which helps your body to eliminate harmful substances, such as ammonia and urea. Additionally, malate is a crucial component of citrulline malate, and plays a key role in energy production within the muscle cells.

What are the Types of Citrulline Supplements in India?

Note: Prices vary widely depending on brand (imported vs. Indian), dosage strength, and form (capsule vs. powder).

The cost of Citrulline supplements in India usually varies depending on the brand, form (powder or capsules), quantity and vendor. In this section, we will highlight the prices of various types of citrulline supplements that are available in India. These are as follows:

L-Citrulline

It is a non-essential amino acid that plays a role in the urea cycle and nitric oxide production. These are mainly found in pure form as a supplement and may be preferable for those seeking a direct boost in nitric oxide synthesis. The cost of these supplements usually ranges between Rs. 259 and Rs. 3,999.

Citrulline Malate

Citulline malate is the combination of L-citrulline and malic acid. Malic acid is an intermediate in the citric acid cycle, which contributes to energy production. These are most commonly used in sports supplements and cost somewhere between Rs. 1,000 and Rs. 4,000.   

What are the Benefits of Citrulline Therapy?

Citrulline therapy, involving L-citrulline supplementation, offers various health benefits, especially in athletes. In this section, we will discuss some of the key benefits of having citrulline therapy.

Improved Blood Flow

Citrulline therapy increases nitric oxide production in the body, which leads to vasodilation (widening of blood vessels) and potentially improves oxygen uptake in muscles. Citrulline supplementation has shown potential benefits in mild erectile dysfunction and blood pressure reduction in small studies, but it should not replace established medical treatments.

Enhanced Athletic Performance

L-citrulline supplements can improve exercise performance, especially in activities like weightlifting and cycling. This usually occurs due to increased oxygen uptake in muscles and reduced muscle soreness after exercise.    

Improve Heart Health

Citrulline malate or L-citrulline supplements are beneficial for individuals suffering from high blood pressure. It promotes healthy blood vessels and potentially lowers blood pressure, which contributes to improved cardiovascular health.

What are the Side Effects of Citrulline Supplements?

While these supplements are generally safe, they can cause side effects, especially with excessive or improper use. Oral supplementation overconsumption may cause several side effects, which we will discuss in this section. Let us discuss them in detail:

• Gastrointestinal Issues: Many individuals report frequent nausea, vomiting, and diarrhoea, especially with high doses.   
• Muscle Cramps: Some individuals may experience muscle cramps, potentially due to electrolyte imbalance or dehydration.  
• Dehydration: Citrulline malate supplements can increase the body’s water requirement, leading to dehydration if fluid intake is not sufficient. 
• Electrolyte Imbalance: Excessive consumption of L-citrulline can interfere with the normal physiology of electrolytes (sodium, potassium, and calcium) in the body. 
• Water Retention: In the early stages of the supplement intake, it may cause transient water retention, leading to bloating.

Citrulline supplements may lead to better performance and heart health, reducing high blood pressure. Additionally, it is crucial to consult with a healthcare professional before starting any new supplement regimen, especially if you have underlying health conditions or are taking other medications.  

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