Did you know that a hidden hormone imbalance could be silently driving your high blood pressure? Aldosterone, which is produced by the adrenal glands, regulates salt and water in the body. However, when the body produces too much aldosterone, it can result in a condition called aldosteronism. Shockingly, a 2020 study found it in over 20% of patients with resistant hypertension.
So, could this be the missing link in your health puzzle? Keep reading to know all the details.
In primary aldosteronism, also known as Conn’s syndrome, excess aldosterone causes the body to retain sodium and water. This increases blood volume, thereby raising blood pressure. At the same time, the body loses excessive potassium, which can result in various symptoms.
There are multiple underlying causes of this condition:
People between the ages of 30 and 50 are more commonly affected, and women may have a slightly increased risk. It is estimated that 5–10% of people with hypertension may have undiagnosed primary aldosteronism. It is particularly prevalent in those whose blood pressure does not improve with standard antihypertensive medicines.
In secondary aldosteronism, elevated aldosterone levels occur as a response to another underlying health condition rather than a problem within the adrenal glands themselves.
Conditions that can trigger this include:
In secondary aldosteronism, the adrenal glands produce excess aldosterone as an appropriate response to another medical condition. This is typically driven by high levels of renin, a kidney enzyme. The elevated aldosterone is a symptom of the underlying problem, not the primary cause.
The most common sign of aldosteronism is resistant hypertension, which is high blood pressure that does not respond well to standard treatment. Additional symptoms can occur, particularly if the condition leads to low potassium levels (hypokalemia). These may include.
If left untreated, aldosteronism can lead to severe complications such as:
The typical diagnosis of this condition includes:
Imaging techniques such as CT or MRI scans help detect adrenal gland abnormalities. In certain cases, adrenal vein sampling is performed to distinguish if one or both adrenal glands are affected.
Some of the treatment options, depending on the underlying cause, are as follows:
Dietary and lifestyle recommendations include:
These steps support blood pressure control, along with medication or surgery. Lifestyle changes can help control blood pressure and prevent serious complications.
Aldosteronism often goes undetected, yet it can be a key contributor to resistant high blood pressure. Early diagnosis and treatment with the help of medication, surgery, and lifestyle changes can significantly improve health outcomes. If your hypertension is not responding to standard care, exploring aldosterone levels might reveal a crucial piece of your health puzzle.