Rheumatic heart disease is a condition that arises from damage to the heart valves after one or more episodes of rheumatic fever. It is caused by the bacteria group A streptococcus. An untreated or poorly throat infection treatment can cause an inflammatory illness with an immune-mediated origin.
Several risk factors lead to the development of RHD. They involve social and environmental conditions, genetic influences, and limited access to healthcare.
Here are some common rheumatic heart disease risk factors, as stated by reputed healthcare providers worldwide:
Living in overcrowded localities with limited access to clean water, sanitation, and healthcare increases the risk of streptococcal infections, which can eventually lead to rheumatic fever and then RHD.
In many low- and middle-income countries, poverty and overcrowding are common, creating conditions where group A streptococcal bacteria can spread easily among children and families. Without early diagnosis and treatment of sore throats, the infection can progress to more serious complications such as rheumatic fever.
Usually, Group A Streptococcus bacteria cause rheumatic fever. Children who suffer repeated episodes of streptococcal sore throat are at greater risk of developing rheumatic fever, especially if they do not receive timely antibiotic treatment.
Similar inflammations can cause permanent damage to the heart valves over time. So, preventing recurrent infections is crucial to reduce the overall risk of rheumatic heart disease.
Many individuals at risk of rheumatic heart disease do not have access to basic healthcare services, including diagnosis and treatment for sore throats or fever. In rural and under-resourced areas, there is often a lack of trained healthcare professionals, medical facilities, and medications.
Without early intervention, minor infections can turn into severe complications. Thus, access to primary care services plays a vital role in the early detection and treatment of rheumatic fever.
Some individuals may have a genetic tendency to develop an exaggerated immune response to streptococcal infections, making them more susceptible to rheumatic fever and subsequent heart damage. Although the hereditary factor alone does not cause the illness, it increases vulnerability when combined with other factors. More research is being conducted to understand the genetic links to this condition.
For some people, RHD typically begins in childhood following an episode of acute rheumatic fever. Children between the ages of 5 and 15 are especially vulnerable, as they are more likely to contract streptococcal throat infections.
Young children living in poorly sanitised or crowded settings are at even higher risk. The damage caused to the heart valves during childhood can persist and worsen in adulthood if not treated properly.
Rheumatic heart disease is largely preventable, but its risk factors have a deep connection to limited access to healthcare and recurrent infections. By addressing these factors through public health efforts, education and timely medical treatment, the global burden of RHD can be significantly reduced.